Our research focuses on developing integrated microfluidic platforms for cell and molecular analysis, enabling precise isolation, detection, and processing of complex biological samples. The system incorporates immunomagnetic techniques for selective separation of target cells such as NK cells, circulating tumor cells (CTCs), and plasma cells. 

By integrating optical and aptamer-based sensing methods within microfluidic devices, the platform enables on-chip biomolecular and metabolite analysis. This approach allows high-throughput processing of microliter-scale samples with minimal preprocessing, supporting applications in diagnostics, immune cell analysis, and bioanalytical systems.

Immune cell separation system

     The system consists of three modules: a mixing module for magnetic labeling of non-target cells, a separation module that removes labeled cells using an external magnetic field, and an activation module that enhances NK cell functionality. The system reduces processing time, minimizes manual handling, and operates efficiently with microliter-scale blood samples. We aim to achieve high purity, recovery, and functionality of NK cells for applications in point-of-care diagnostics and immunotherapy.

Our research focuses on developing microfluidic biorefinery platforms for microalgae, enabling precise control of growth conditions and efficient analysis of metabolic products. The system integrates on-chip cultivation with dynamic regulation of environmental parameters, including light, flow, and nutrient conditions.

The platform supports real-time monitoring of biomass and metabolite production through integrated sensing systems, while enhancing productivity via controlled external stimulation. This approach provides a scalable solution for high-throughput screening and sustainable bioenergy and biochemical production.

Our research focuses on developing microfluidic organ-on-a-chip platforms that replicate key physiological functions of human tissues, particularly for neuroscience applications. These systems enable controlled microenvironments for studying neural networks, including myelination, neural stem cell differentiation, and neural circuit formation.

The platform includes compartmentalized microfluidic systems for axon regeneration studies and in vitro blood barrier models such as the blood–brain-barrier (BBB) and blood–retina-barrier (BRB). Integrated stimulation and sensing capabilities allow dynamic investigation of tissue functionality and biological responses.