Our research focuses on developing an integrated microfluidic platform for NK cell processing, enabling direct isolation and activation of NK cells from whole blood within a single device.

     The system consists of three modules: a mixing module for magnetic labeling of non-target cells, a separation module that removes labeled cells using an external magnetic field, and an activation module that enhances NK cell functionality.

     By integrating these processes into a Lab-on-a-Chip platform, the system reduces processing time, minimizes manual handling, and operates efficiently with microliter-scale blood samples. We aim to achieve high purity, recovery, and functionality of NK cells for applications in point-of-care diagnostics and immunotherapy.

     Our research focuses on developing microfluidic Organ-on-a-chip systems that replicate key physiological functions of human tissues, including brain, retina, and blood–brain barrier (BBB) models. By integrating controlled microenvironments with engineered cell culture platforms, we aim to mimic in vivo-like conditions at the chip scale.

     The platform enables 3D cell culture, precise control of cellular interactions, and real-time monitoring of biological responses. Integrated electrical and chemical stimulation further allows dynamic studies of tissue functionality and drug responses.

     This Lab-on-a-Chip approach provides a versatile platform for disease modeling, drug screening, and next-generation biomedical applications.